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Phenotypes Associated with This Genotype
Genotype
MGI:5515811
Allelic
Composition		 Sox10tm7.1(Sox10)Weg/Sox10+
Tg(Tyr-cre/ERT2)13Bos/0
Tg(Tyr-NRAS*Q61K)1Bee/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J * DBA/2 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox10tm7.1(Sox10)Weg mutation (0 available); any Sox10 mutation (31 available)
Tg(Tyr-cre/ERT2)13Bos mutation (12 available)
Tg(Tyr-NRAS*Q61K)1Bee mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
pigmentation phenotype ( J:193443 )
N
• mice injected with tamoxifen at 2 months of age do not exhibit hyperpigmentation in the back skin, snout and paws at 12 months of age, indicating reversion of lesions that are seen in single Tg(Tyr-NRAS*Q61K)1Bee mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory