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Phenotypes Associated with This Genotype
Genotype
MGI:5504499
Allelic
Composition		 Ctnna1tm1Efu/Ctnna1tm1Efu
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
Genetic
Background		 involves: 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A1cfTg(Myh6-cre/Esr1*)1Jmk mutation (5 available); any A1cf mutation (37 available)
Ctnna1tm1Efu mutation (1 available); any Ctnna1 mutation (134 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
dilated cardiomyopathy ( J:197814 )
• progressive 8 months after tamoxifen treatment

muscle
dilated cardiomyopathy ( J:197814 )
• progressive 8 months after tamoxifen treatment

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory