Phenotypes for Apoe Arhgef26 MGI:5500052 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Apoe^tm1Unc/Apoe^tm1Unc Arhgef26^tm1.1Kbur/Arhgef26^tm1.1Kbur
Genetic Background	B6.Cg-Arhgef26^tm1.1Kbur Apoe^tm1Unc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoe^tm1Unc mutation (34 available); any Apoe mutation (163 available)
Arhgef26^tm1.1Kbur mutation (0 available); any Arhgef26 mutation (49 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

decreased susceptibility to atherosclerosis ( J:195919 )

• in the aortic arch descending thoracic aorta of mice fed a western diet compared with Apoe^tm1Unc homozygotes

• however, mice fed standard chow do not exhibit a significant difference

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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