Phenotypes for Epx Gt(ROSA)26Sor MGI:5500049 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Epx^{tm1.1(cre)Jlee}/Epx⁺ Gt(ROSA)26Sor^tm1(DTA)Lky/Gt(ROSA)26Sor⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epx^{tm1.1(cre)Jlee} mutation (0 available); any Epx mutation (30 available)
Gt(ROSA)26Sor^tm1(DTA)Lky mutation (3 available); any Gt(ROSA)26Sor mutation (1098 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

decreased eosinophil cell number ( J:198489 )

• peripheral blood is deficient in eosinophils relative to wild-type (0.19% vs 1.85%)

• other non-eosinophilic circulating cell populations are unchanged in cell number and relative composition in mutants

immune system

decreased eosinophil cell number ( J:198489 )

• peripheral blood is deficient in eosinophils relative to wild-type (0.19% vs 1.85%)

• other non-eosinophilic circulating cell populations are unchanged in cell number and relative composition in mutants

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24