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Phenotypes Associated with This Genotype
Genotype
MGI:5496427
Allelic
Composition		 Eef1a1tm2Arge/Eef1a1+
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic
Background		 involves: C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eef1a1tm2Arge mutation (0 available); any Eef1a1 mutation (60 available)
Gt(ROSA)26Sortm9(cre/ESR1)Arte mutation (3 available); any Gt(ROSA)26Sor mutation (1060 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal bone marrow cell physiology ( J:196407 )
• leukemia-initiating cells plated in methylcellulose cultures in the presence of tamoxifen exhibit decreased blast colony number and loss of blast colony formation due to increased apoptosis compared with control cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory