Phenotypes for Brca1 Cd19 MGI:5495977 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Brca1^tm2Cxd/Brca1^tm2Cxd Cd19^tm1(cre)Cgn/Cd19⁺
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Brca1^tm2Cxd mutation (3 available); any Brca1 mutation (113 available)
Cd19^tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

chromosome breakage ( J:197442 )

• cells treated with PARP-inhibition exhibit increased chromosomal damage compared with wild-type cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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