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Phenotypes Associated with This Genotype
Genotype
MGI:5486305
Allelic
Composition		 Wasltm2Sbs/Wasltm2Sbs
Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Six2tm1(tTA,tetO-EGFP/cre)Amc mutation (0 available); any Six2 mutation (19 available)
Wasltm2Sbs mutation (0 available); any Wasl mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Hypoplasia and loss of glomeruli and proximal tubules in Wasltm2Sbs/Wasltm2Sbs Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ kidneys

renal/urinary system
decreased renal tubule number ( J:195266 )
• decrease in proximal tubule numbers at P0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory