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Phenotypes Associated with This Genotype
Genotype
MGI:5484587
Allelic
Composition		 Cd74tm1Liz/Cd74tm1Liz
Sppl2atm1Dgen/Sppl2atm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd74tm1Liz mutation (5 available); any Cd74 mutation (38 available)
Sppl2atm1Dgen mutation (0 available); any Sppl2a mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:194595 )
N
• mice exhibit normalized numbers of T2 B cells, marginal zone B cells and myeloid dendritic cells

hematopoietic system

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory