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Phenotypes Associated with This Genotype
Genotype
MGI:5484530
Allelic
Composition		 Blmtm4Ches/Blmtm4Ches
Trp53bp1tm1Jc/Trp53bp1tm1Jc
Cd19tm1(cre)Cgn/Cd19+
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Blmtm4Ches mutation (1 available); any Blm mutation (87 available)
Cd19tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)
Trp53bp1tm1Jc mutation (1 available); any Trp53bp1 mutation (100 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal class switch recombination ( J:194603 )
• increased switching to a small extent compared with Trp53bp1tm1Jc homozygotes

hematopoietic system
abnormal class switch recombination ( J:194603 )
• increased switching to a small extent compared with Trp53bp1tm1Jc homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory