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Phenotypes Associated with This Genotype
Genotype
MGI:5476713
Allelic
Composition		 Map3k8tm1.1Gkl/Map3k8tm1.1Gkl
Lyz2tm1(cre)Ifo/Lyz2+
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyz2tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (41 available)
Map3k8tm1.1Gkl mutation (1 available); any Map3k8 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:193546 )
N
• mice treated with AOM/DSS exhibit normal body weight loss, decreased colon length, inflammation and tissue damage

neoplasm
neoplasm ( J:193546 )
N
• mice treated with AOM/DSS exhibit normal tumor formation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory