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Phenotypes Associated with This Genotype
Genotype
MGI:5475002
Allelic
Composition		 Igkctm1(IGKC)Mnz/Rr166tm4.1Wtg
Genetic
Background		 involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igkctm1(IGKC)Mnz mutation (2 available); any Igkc mutation (9 available)
Rr166tm4.1Wtg mutation (0 available); any Rr166 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal B cell physiology ( J:193015 )
• slight preferential usage of the deleted mouse allele rather than the inserted human allele
abnormal immunoglobulin level ( J:193015 )
• slight preferential usage of the deleted mouse allele rather than the inserted human allele

hematopoietic system
abnormal B cell physiology ( J:193015 )
• slight preferential usage of the deleted mouse allele rather than the inserted human allele
abnormal immunoglobulin level ( J:193015 )
• slight preferential usage of the deleted mouse allele rather than the inserted human allele

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory