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Phenotypes Associated with This Genotype
Genotype
MGI:5474059
Allelic
Composition
Adam10tm2Psa/Adam10tm2Psa
Tg(Serpinb7-icre)1Fech/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adam10tm2Psa mutation (1 available); any Adam10 mutation (39 available)
Tg(Serpinb7-icre)1Fech mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
N
• mice do not show overt abnormalities, even though cre expression is detected in esophagus and the stomach; no differences in histology are detected in esophagus and glandular hindstomach relative to controls
• mice grow at similar rate to littermates, as shown by body weight measurements
• forestomach hypoplasia is detected with decreased depth of gastric pits in adult mice
• no digestive problems are observed


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory