Phenotypes for Gt(ROSA)26Sor Tbx5 Tg(Kcne1-cre/ERT2)1Imos MGI:5474054 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Tbx5^tm1.2Jse/Tbx5^tm1.2Jse Tg(Kcne1-cre/ERT2)1Imos/0
Genetic Background	involves: 129S4/SvJaeSor * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1Sor mutation (10 available); any Gt(ROSA)26Sor mutation (1062 available)
Tbx5^tm1.2Jse mutation (0 available); any Tbx5 mutation (30 available)
Tg(Kcne1-cre/ERT2)1Imos mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:190765 )

N	• tamoxifen-treated mutants have ventricular conduction system (VCS) cellular fate maps indistinguishable from Tbx5-sufficient animals indicating that defects in conditional animals do not result from loss of VCS cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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