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Phenotypes Associated with This Genotype
Genotype
MGI:5470096
Allelic
Composition		 Atg7tm1Tchi/Atg7tm1Tchi
Tg(SLC18A3-cre)KMisa/0
Genetic
Background		 involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atg7tm1Tchi mutation (3 available); any Atg7 mutation (52 available)
Tg(SLC18A3-cre)KMisa mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:193770 )
N
• mice exhibit normal motor function

nervous system
abnormal motor neuron morphology ( J:193770 )
• with amorphous structures and large inclusions at 2 years of age
• however, there is no loss of motor neurons

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory