behavior/neurological
N |
• unlike Scyl1tm1.1Spel homozygotes, mice do not develop tremors and the majority do not become paralyzed
|
• motor dysfunctions develop more slowly and are not as severe as in Scyl1tm1.1Spel homozygotes
|
• by 4 weeks
|
• posterior waddle by 8 weeks
|
• by 8 weeks
|
muscle
N |
• unlike Scyl1tm1.1Spel homozygotes, mice do not develop massive muscle wasting
|
nervous system
microgliosis
(
J:192445
)
astrocytosis
(
J:192445
)
• slight
|
growth/size/body
skeleton
N |
• unlike Scyl1tm1.1Spel homozygotes, mice do not develop flattening of the pelvis
|
cardiovascular system
hematopoietic system
microgliosis
(
J:192445
)
immune system
microgliosis
(
J:192445
)