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Phenotypes Associated with This Genotype
Genotype
MGI:5469881
Allelic
Composition		 Pknox1tm2.1Fbla/Pknox1tm2.1Fbla
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(cre/ERT2)Brn mutation (1 available); any Gt(ROSA)26Sor mutation (1062 available)
Pknox1tm2.1Fbla mutation (0 available); any Pknox1 mutation (90 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased pro-B cell number ( J:192251 )
• in tamoxifen-treated mice
decreased pre-B cell number ( J:192251 )
• in tamoxifen-treated mice

immune system
increased pro-B cell number ( J:192251 )
• in tamoxifen-treated mice
decreased pre-B cell number ( J:192251 )
• in tamoxifen-treated mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory