Phenotypes Associated with This Genotype

Genotype
MGI:5468335

• Allelic Composition: a/a; Mlph^ln/Mlph^ln
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

abnormal coat/hair pigmentation ( J:12970 )

• this genotype is indistinguishable from homozygous nonagouti, Myo5a^d mice

abnormal hair follicle melanocyte morphology ( J:12970 )

• pigment bearing cells have fewer and thinner dendritic processes than wild-type melanocytes

• abnormality of shape results in clumping of melanin granules

abnormal hair shaft melanin granule distribution ( J:12970 )

• melanin granules are clumped into large masses due to the shape of the melanocytes

diluted coat color ( J:12970 )

• this genotype is indistinguishable from homozygous nonagouti, Myo5a^d mice

pigmentation

abnormal coat/hair pigmentation ( J:12970 )

• this genotype is indistinguishable from homozygous nonagouti, Myo5a^d mice

abnormal hair follicle melanocyte morphology ( J:12970 )

• pigment bearing cells have fewer and thinner dendritic processes than wild-type melanocytes

• abnormality of shape results in clumping of melanin granules

abnormal hair shaft melanin granule distribution ( J:12970 )

• melanin granules are clumped into large masses due to the shape of the melanocytes

diluted coat color ( J:12970 )

• this genotype is indistinguishable from homozygous nonagouti, Myo5a^d mice