Phenotypes Associated with This Genotype

Genotype
MGI:5467307

• Allelic Composition: Pten^tm2.1Ppp/Pten^tm2.1Ppp; Tg(Osr1-cre)4Mrt/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased prostate intraepithelial neoplasia incidence ( J:192348 )

♂ • PIN is seen in 31% of prostate ducts as early as 2 weeks of age, in 66% of ducts at 4 weeks, and 79% of ducts at 9 months of age show extensive high-grade PIN

reproductive system

increased prostate intraepithelial neoplasia incidence ( J:192348 )

♂ • PIN is seen in 31% of prostate ducts as early as 2 weeks of age, in 66% of ducts at 4 weeks, and 79% of ducts at 9 months of age show extensive high-grade PIN

endocrine/exocrine glands

increased prostate intraepithelial neoplasia incidence ( J:192348 )

♂ • PIN is seen in 31% of prostate ducts as early as 2 weeks of age, in 66% of ducts at 4 weeks, and 79% of ducts at 9 months of age show extensive high-grade PIN