About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5467291
Allelic
Composition		 Sirt2tm1Gdon/Sirt2tm1Gdon
Tg(HDexon1)62Gpb/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sirt2tm1Gdon mutation (0 available); any Sirt2 mutation (29 available)
Tg(HDexon1)62Gpb mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired coordination ( J:193012 )
• as in Tg(HDexon1)62Gpb mice
decreased grip strength ( J:193012 )
• as in Tg(HDexon1)62Gpb mice

nervous system
decreased brain weight ( J:193012 )
• as in Tg(HDexon1)62Gpb mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory