Phenotypes for Atmin Bcl2l11 Cd79a MGI:5463975 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Bcl2l11^tm1.1Ast/Bcl2l11^tm1.1Ast Cd79a^tm1(cre)Reth/Cd79a⁺
Genetic Background	involves: 129S1/Sv * BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atmin^tm1.2Jhh mutation (4 available); any Atmin mutation (39 available)
Bcl2l11^tm1.1Ast mutation (5 available); any Bcl2l11 mutation (37 available)
Cd79a^tm1(cre)Reth mutation (3 available); any Cd79a mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:191832 )

N	• B cell development is rescued compared with Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

enlarged spleen ( J:191832 )

• compared with control and Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

increased spleen weight ( J:191832 )

• compared with control and Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

increased B cell number ( J:191832 )

• compared with control and Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

increased immature B cell number ( J:191832 )

• compared with Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

increased pre-B cell number ( J:191832 )

• compared with Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

hematopoietic system

enlarged spleen ( J:191832 )

• compared with control and Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

increased spleen weight ( J:191832 )

• compared with control and Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

increased B cell number ( J:191832 )

• compared with control and Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

increased immature B cell number ( J:191832 )

• compared with Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

increased pre-B cell number ( J:191832 )

• compared with Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

growth/size/body

enlarged spleen ( J:191832 )

• compared with control and Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

increased spleen weight ( J:191832 )

• compared with control and Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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