About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5463975
Allelic
Composition		 Atmintm1.2Jhh/Atmintm1.2Jhh
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Cd79atm1(cre)Reth/Cd79a+
Genetic
Background		 involves: 129S1/Sv * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atmintm1.2Jhh mutation (4 available); any Atmin mutation (39 available)
Bcl2l11tm1.1Ast mutation (5 available); any Bcl2l11 mutation (37 available)
Cd79atm1(cre)Reth mutation (3 available); any Cd79a mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:191832 )
N
• B cell development is rescued compared with Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
enlarged spleen ( J:191832 )
• compared with control and Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
increased spleen weight ( J:191832 )
• compared with control and Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
increased B cell number ( J:191832 )
• compared with control and Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
increased immature B cell number ( J:191832 )
• compared with Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
increased pre-B cell number ( J:191832 )
• compared with Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice

hematopoietic system
enlarged spleen ( J:191832 )
• compared with control and Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
increased spleen weight ( J:191832 )
• compared with control and Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
increased B cell number ( J:191832 )
• compared with control and Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
increased immature B cell number ( J:191832 )
• compared with Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
increased pre-B cell number ( J:191832 )
• compared with Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice

growth/size/body
enlarged spleen ( J:191832 )
• compared with control and Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice
increased spleen weight ( J:191832 )
• compared with control and Atmintm1.2Jhh/Atmintm1.2Jhh Cd79atm1(cre)Reth/Cd79a+ mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory