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Phenotypes Associated with This Genotype
Genotype
MGI:5463971
Allelic
Composition		 Atmintm1.2Jhh/Atmintm1.2Jhh
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atmintm1.2Jhh mutation (4 available); any Atmin mutation (38 available)
Tg(Mx1-cre)1Cgn mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:191832 )
N
• pIpC-treated mice exhibit normal T cell development
decreased lymphocyte cell number ( J:191832 )
• 2-fold in pIpC-treated mice
decreased B cell number ( J:191832 )
• in pIpC-treated mice
decreased mature B cell number ( J:191832 )
• in the bone marrow of pIpC-treated mice
• 2-fold in the spleen of pIpC-treated mice
decreased pre-B cell number ( J:191832 )
• in the bone marrow of pIpC-treated mice

hematopoietic system
decreased erythrocyte cell number ( J:191832 )
• modest in pIpC-treated mice
decreased lymphocyte cell number ( J:191832 )
• 2-fold in pIpC-treated mice
decreased B cell number ( J:191832 )
• in pIpC-treated mice
decreased mature B cell number ( J:191832 )
• in the bone marrow of pIpC-treated mice
• 2-fold in the spleen of pIpC-treated mice
decreased pre-B cell number ( J:191832 )
• in the bone marrow of pIpC-treated mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory