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Phenotypes Associated with This Genotype
Genotype
MGI:5461495
Allelic
Composition		 Gadd45gtm1Jni/Gadd45g+
Map3k4tm1Flv/Map3k4+
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gadd45gtm1Jni mutation (0 available); any Gadd45g mutation (11 available)
Map3k4tm1Flv mutation (1 available); any Map3k4 mutation (79 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal testis development ( J:191096 )
• significant numbers of Stra8-positive meiotic germ cells are detectable at the poles of XY gonads at E14.5 indicating a activation of ovarian pathways

reproductive system
abnormal testis development ( J:191096 )
• significant numbers of Stra8-positive meiotic germ cells are detectable at the poles of XY gonads at E14.5 indicating a activation of ovarian pathways

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory