Phenotypes Associated with This Genotype

Genotype
MGI:5449898

• Allelic Composition: Tg(SOD1)2Gur/0; Tg(SOD1*G93A)1Gur/0
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:109458 )

• lifespan is on average 117.7 days

nervous system

abnormal nervous system physiology ( J:109458 )

• mutants exhibit exacerbated amyotrophic lateral sclerosis-like phenotypes compared to single Tg(SOD1*G93A)1Gur mice, with onset of disease on average at 76.8 days of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
amyotrophic lateral sclerosis type 1		DOID:0060193	OMIM:105400	J:109458