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Phenotypes Associated with This Genotype
Genotype
MGI:5447643
Allelic
Composition		 Atp7atm1.1Mjp/Atp7a+
Cldn6tm1(cre)Dkwu/Cldn6+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp7atm1.1Mjp mutation (0 available); any Atp7a mutation (69 available)
Cldn6tm1(cre)Dkwu mutation (1 available); any Cldn6 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Patches of hypopigmentation in coats of Atp7atm1.1Mjp/Atp7a+ Cldn6tm1(cre)Dkwu/Cldn6+ females

mortality/aging
postnatal lethality, incomplete penetrance ( J:189931 )
• only two mice survive beyond the second day after birth
prenatal lethality, incomplete penetrance ( J:189931 )
• fewer than expected mice are born

integument

pigmentation
hypopigmentation ( J:189931 )
• mosaic pattern of hypopigmented coat coloring in surviving mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory