About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5445989
Allelic
Composition		 Cdh5tm1Dvst/Cdh5tm1Dvst
Tg(Cdh5-cre/ERT2)1Rha/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh5tm1Dvst mutation (0 available); any Cdh5 mutation (53 available)
Tg(Cdh5-cre/ERT2)1Rha mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal retina vasculature morphology ( J:189010 )
• prominent endothelial hyper-sprouting
• detaching tip cells have poor cellular connections to the vascular plexus at the angiogenic front and show signs of increased motility

vision/eye
abnormal retina vasculature morphology ( J:189010 )
• prominent endothelial hyper-sprouting
• detaching tip cells have poor cellular connections to the vascular plexus at the angiogenic front and show signs of increased motility

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory