Phenotypes for Ctnnb1 Gt(ROSA)26Sor H2az2 MGI:5440183 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ctnnb1^tm2Kem/Ctnnb1^tm2.1Kem Gt(ROSA)26Sor^{tm1(Ctnnb1)Kem}/Gt(ROSA)26Sor⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
Genetic Background	involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm2.1Kem mutation (0 available); any Ctnnb1 mutation (51 available)
Ctnnb1^tm2Kem mutation (1 available); any Ctnnb1 mutation (51 available)
Gt(ROSA)26Sor^{tm1(Ctnnb1)Kem} mutation (0 available); any Gt(ROSA)26Sor mutation (1062 available)
H2az2^{Tg(Wnt1-cre)11Rth} mutation (2 available); any H2az2 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:187739 )

nervous system

abnormal brain morphology ( J:187739 )

• brain defects

craniofacial

abnormal craniofacial morphology ( J:187739 )

• impaired morphogenesis of craniofacial structures

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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