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Phenotypes Associated with This Genotype
Genotype
MGI:5440080
Allelic
Composition		 Bmal1tm1.1Ljm/Bmal1tm1.1Ljm
Tmem163Tg(ACTB-cre)2Mrt/0
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmal1tm1.1Ljm mutation (0 available); any Bmal1 mutation (139 available)
Tmem163Tg(ACTB-cre)2Mrt mutation (3 available); any Tmem163 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased locomotor activity ( J:188253 )
• mice show lower activity overall compared to controls
abnormal circadian behavior ( J:188253 )
• mice are arrhythmic in constant darkness whereas cre-negative floxed mice are rhythmic under 12-12h light dark conditons and constant darkness

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory