About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5438795
Allelic
Composition		 Tg(Camk2a-tTA)1Mmay/0
Fgf14Tg(tetO-MAPT*P301L)4510Kha/Fgf14+
Genetic
Background		 involves: 129/Sv * C57BL/6 * CBA * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf14Tg(tetO-MAPT*P301L)4510Kha mutation (2 available); any Fgf14 mutation (40 available)
Tg(Camk2a-tTA)1Mmay mutation (8 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dentate gyrus morphology ( J:185792 )
• progressive atrophy of dentate granule cells
hippocampal neuron degeneration ( J:185792 )
• progressive atrophy of hippocampal pyramidal neurons

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory