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Phenotypes Associated with This Genotype
Genotype
MGI:5438774
Allelic
Composition		 Fgf10tm1.1(cre/ERT2)Sbel/Fgf10tm1.1(cre/ERT2)Sbel
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf10tm1.1(cre/ERT2)Sbel mutation (1 available); any Fgf10 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
absent lung buds ( J:187831 )
• embryos display complete lung agenesis by E12.5

limbs/digits/tail
decreased limb number ( J:187831 )
• embryos display complete limb agenesis by E12.5

digestive/alimentary system
cecal atresia ( J:187831 )
• observed at E12.5
colon atresia ( J:187831 )
• embryos show colonic atresia by E12.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory