Phenotypes Associated with This Genotype

Genotype
MGI:5432789

• Allelic Composition: Cntf^tm1Vlcg/Cntf^tm1Vlcg
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:186611 )

N • neuron migration in the rostral migratory stream is normal

abnormal neuron proliferation ( J:186611 )

• adult neuron proliferation in the subventricular zone nuclei is reduced compared to in wild-type mice

• after quipirole or 6-OHDA treatment, adult neuron proliferation in the subventricular zone nuclei is not alter unlike in wild-type mice

decreased neuronal precursor cell number ( J:186611 )

• in the subventricular zone nuclei of quinpirole-treated mice

cellular

abnormal neuron proliferation ( J:186611 )

• adult neuron proliferation in the subventricular zone nuclei is reduced compared to in wild-type mice

• after quipirole or 6-OHDA treatment, adult neuron proliferation in the subventricular zone nuclei is not alter unlike in wild-type mice