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Phenotypes Associated with This Genotype
Genotype
MGI:5432562
Allelic
Composition		 Lama5tm3Jhm/Lama5tm3Jhm
Tg(NPHS2-rtTA2*M2)1Jbk/0
Tg(tetO-LAMA5)1Jhm/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lama5tm3Jhm mutation (0 available); any Lama5 mutation (155 available)
Tg(NPHS2-rtTA2*M2)1Jbk mutation (1 available)
Tg(tetO-LAMA5)1Jhm mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal/urinary system phenotype ( J:185850 )
N
• when doxycycline is administered from E12 to E15 to pregnant animals, offspring do not develop proteinuria or hematuria, with no kidney disease at least to 6 months of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory