Phenotypes Associated with This Genotype

Genotype
MGI:5431216

• Allelic Composition: Ptbp2^{Gt(NPX210)Byg}/Ptbp2^{Gt(NPX210)Byg}
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality ( J:185949 )

nervous system

abnormal neuron differentiation ( J:185949 )

• abnormal neural stem cell polarity

premature neuronal precursor differentiation ( J:185949 )

• premature neurogenesis

abnormal cortical ventricular zone morphology ( J:185949 )

• mislocalization of S-phase cells with small ectopic clusters of proliferating cells in the lateral wall of the ventricular zone

decreased neuronal precursor cell number ( J:185949 )

cellular

abnormal neuron differentiation ( J:185949 )

• abnormal neural stem cell polarity

premature neuronal precursor differentiation ( J:185949 )

• premature neurogenesis