Phenotypes Associated with This Genotype

Genotype
MGI:5430383

• Allelic Composition: Ugdh^tm1.1Xzh/Ugdh^tm1.1Xzh; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
• Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:185652 )

• die at birth

endocrine/exocrine glands

abnormal lacrimal gland development ( J:185652 )

• disruption of lacrimal gland budding

absent lacrimal glands ( J:185652 )

• at E14.5 and at birth

embryo

abnormal embryonic tissue physiology ( J:185652 )

• disruption of glycosaminoglycan biosynthesis in the periocular mesenchyme

digestive/alimentary system

cleft palate ( J:185652 )

craniofacial

cleft palate ( J:185652 )

vision/eye

abnormal lacrimal gland development ( J:185652 )

• disruption of lacrimal gland budding

absent lacrimal glands ( J:185652 )

• at E14.5 and at birth

growth/size/body

cleft palate ( J:185652 )