Phenotypes for Dll1 Foxa2 MGI:5428768 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Dll1^tm1.1Hri/Dll1^tm1.1Hri Foxa2^{tm3.1(icre)Heli}/Foxa2⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dll1^tm1.1Hri mutation (0 available); any Dll1 mutation (46 available)
Foxa2^{tm3.1(icre)Heli} mutation (0 available); any Foxa2 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal pancreas development ( J:184814 )

• at E10.5, an excessive formation of glucagon +ve cells is observed

• reduced numbers of Nkx6-1+ve Ptf1a-ve cells are detected at E12.5

• however, no apparent defects in proximal-distal patterning in E15.5 and E18.5 embryos are observed

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23