Phenotypes Associated with This Genotype

Genotype
MGI:5427619

• Allelic Composition: Fuom^tm1Ckp/Fuom^tm1Ckp
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:185112 )

• minor

abnormal sexual interaction ( J:185112 )

♀ • ovariectomized mice exhibit masculinized coital behaviors compared with control mice

♀ • intact and ovariectomized female mice prefer female urine unlike control mice

♀ • however, masculinized coital behaviors are rescued by 17beta-estradiol treatment

abnormal mating receptivity ( J:185112 )

♀ • female mice avoid normal male partners

♀ • ovariectomized mice treated with 17beta-estradiol exhibit reduced sexual receptivity (noted by lordosis) with occasional mating by forced intromission compared with control mice

growth/size/body

decreased body weight ( J:185112 )

• slight

skeleton

abnormal spine curvature ( J:185112 )

• ovariectomized mice exhibit a suppression of lordosis induced by 17beta-estradiol treatment compared with control mice