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Phenotypes Associated with This Genotype
Genotype
MGI:5427584
Allelic
Composition
Pik3catm1.1Waph/Pik3ca+
Genetic
Background
involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pik3catm1.1Waph mutation (0 available); any Pik3ca mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Hyperproliferation of the ovarian surface epithelium in Pik3catm1.1Waph/Pik3catm1.1Waph mice

cellular
• in mouse embryonic fibroblasts after cre-expressing adenovirus infection
• in mouse embryonic fibroblasts after cre-expressing adenovirus infection

reproductive system
• the ovarian surface epithelium of mice infected with a cre-expressing adenovirus exhibit mild, focal papillary serous hyperplasia compared with control mice

endocrine/exocrine glands
• the ovarian surface epithelium of mice infected with a cre-expressing adenovirus exhibit mild, focal papillary serous hyperplasia compared with control mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory