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Phenotypes Associated with This Genotype
Genotype
MGI:5427454
Allelic
Composition
Hprt1tm86(NR2E1,bEMS223)Ems/Y
Nr2e1frc/Nr2e1frc
Genetic
Background
involves: 129P2/OlaHsd * 129S1/SvImJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hprt1tm86(NR2E1,bEMS223)Ems mutation (0 available); any Hprt1 mutation (1280 available)
Nr2e1frc mutation (2 available); any Nr2e1 mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• decreased in the lateral ventricle and dentate gyrus
• decrease in size that is not as severe as in Nr2e1frc homozygotes
• not as severe as in Nr2e1frc homozygotes

cardiovascular system
N
• mice exhibit normal numbers of retinal vessels and radial symmetry unlike Nr2e1frc homozygotes

vision/eye
N
• mice exhibit normal retina morphology and physiology unlike Nr2e1frc homozygotes

cellular
• decreased in the lateral ventricle and dentate gyrus


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory