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Phenotypes Associated with This Genotype
Genotype
MGI:5427453
Allelic
Composition		 Hprt1tm86(NR2E1,bEMS223)Ems/Y
Genetic
Background		 B6.Cg-Hprt1tm86(NR2E1,bEMS223)Ems
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hprt1tm86(NR2E1,bEMS223)Ems mutation (0 available); any Hprt1 mutation (1274 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:183689 )
N
• mice exhibit normal olfactory bulb and cerebrum size
abnormal neuronal precursor proliferation ( J:183689 )
• decreased in the lateral ventricle and dentate gyrus

cardiovascular system
cardiovascular system phenotype ( J:183689 )
N
• mice exhibit normal numbers of retinal vessels and radial symmetry

vision/eye
vision/eye phenotype ( J:183689 )
N
• mice exhibit normal retina morphology and physiology

cellular
abnormal neuronal precursor proliferation ( J:183689 )
• decreased in the lateral ventricle and dentate gyrus

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory