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Phenotypes Associated with This Genotype
Genotype
MGI:5320167
Allelic
Composition
Tg(CEPHY230E8)50Hgc/0
Genetic
Background
(C57BL/6 x FVB/N)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CEPHY230E8)50Hgc mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• in the reverse platform test of the Morris water maze, mutants show decreases in latency to find the novel position for the invisible platform, however this decrease is less than seen in controls, indicating a learning deficit
• in the reverse probe test, mutants spend the same amount of time as controls in the quadrant of the pool where the reversed platform had been located, however mutants cross the position of the platform much less frequently

nervous system
• mutants exhibit greater cerebral cortical neuronal density than controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory