Phenotypes Associated with This Genotype

Genotype
MGI:5319652

• Allelic Composition: Ctnnb1^tm1Mmt/Ctnnb1⁺; Tg(Col1a1-cre)1Kry/0
• Genetic Background: involves: 129X1/SvJ * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality at weaning, complete penetrance ( J:98430 )

• normal for the first two weeks after birth but die within a few days after weaning

craniofacial

absent lower incisors ( J:98430 )

• form but fail to erupt

skeleton

absent lower incisors ( J:98430 )

• form but fail to erupt

decreased osteoclast cell number ( J:98430 )

increased osteoma incidence ( J:98430 )

• benign tumors in the ribs of 80% of mice

increased bone mass ( J:98430 )

neoplasm

increased osteoma incidence ( J:98430 )

• benign tumors in the ribs of 80% of mice

hematopoietic system

decreased osteoclast cell number ( J:98430 )

immune system

decreased osteoclast cell number ( J:98430 )

growth/size/body

absent lower incisors ( J:98430 )

• form but fail to erupt