About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5319080
Allelic
Composition
Tbxa2rtm1Cof/Tbxa2rtm1.1Bhk
Tg(Tagln-cre)1Her/0
Genetic
Background
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbxa2rtm1.1Bhk mutation (1 available); any Tbxa2r mutation (20 available)
Tbxa2rtm1Cof mutation (0 available); any Tbxa2r mutation (20 available)
Tg(Tagln-cre)1Her mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
respiratory system
• mice exposed to increasing doses of thromboxane receptor agonist U-46619 exhibit an attenuated dose-dependent increase in airway resistance unlike control mice
• mice exposed to U-46619 and methacholine exhibit less of an increased in airway resistance compared with control mice
• however, mice exposed ovalbumin and U-46619 exhibit dose-dependent increase in airway resistance


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/28/2026
MGI 6.24
The Jackson Laboratory