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Phenotypes Associated with This Genotype
Genotype
MGI:5317889
Allelic
Composition		 Apoetm1Unc/Apoetm1Unc
Ccr1tm1Gao/Ccr1tm1Gao
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (34 available); any Apoe mutation (163 available)
Ccr1tm1Gao mutation (9 available); any Ccr1 mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
atherosclerotic lesions ( J:128063 )
• increased plaque size on a high fat diet

immune system
increased interferon-gamma secretion ( J:128063 )
• increased number of secreting cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory