Phenotypes for H2az2 Ror1 Ror2 MGI:5315491 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Ror1^tm1.1Meg/Ror1^tm1.1Meg Ror2^tm1.1Meg/Ror2^tm1.1Meg H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
Genetic Background	involves: 129S4/SvJae * C57BL/6J * CBA/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2^{Tg(Wnt1-cre)11Rth} mutation (2 available); any H2az2 mutation (25 available)
Ror1^tm1.1Meg mutation (1 available); any Ror1 mutation (58 available)
Ror2^tm1.1Meg mutation (1 available); any Ror2 mutation (124 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Ror1^tm1.1Meg/Ror1^tm1.1Meg Ror2^tm1.1Meg/Ror2^tm1.1Meg H2az2^{Tg(Wnt1-cre)11Rth}/0 embryos exhibit sympathetic axon branching defects

nervous system

abnormal sympathetic neuron innervation pattern ( J:182150 )

• sympathetic innervation defects are seen in several target organs at E17.5

• defects are similar to those in Wnt5a null mice

• however, sympathetic chain ganglia appear grossly intact

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24