Phenotypes for Hesx1 Tcf7l1 MGI:5314534 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hesx1^tm1(cre)Jpmb/Hesx1⁺ Tcf7l1^tm1Efu/Tcf7l1^tm2Efu
Genetic Background	involves: 129S/SvEv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hesx1^tm1(cre)Jpmb mutation (0 available); any Hesx1 mutation (14 available)
Tcf7l1^tm1Efu mutation (0 available); any Tcf7l1 mutation (84 available)
Tcf7l1^tm2Efu mutation (0 available); any Tcf7l1 mutation (84 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

microphthalmia ( J:181005 )

• unilateral in some mice

• bilateral in some mice

anophthalmia ( J:181005 )

• unilateral in some mice

• bilateral in some mice

nervous system

small embryonic telencephalon ( J:181005 )

• in some mice

decreased forebrain size ( J:181005 )

• severe truncation in some mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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