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Phenotypes Associated with This Genotype
Genotype
MGI:5311182
Allelic
Composition		 Lhx2tm1.1Lcar/Lhx2tm1.1Lcar
Tg(Lhx2-cre)1Lcar/0
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lhx2tm1.1Lcar mutation (0 available); any Lhx2 mutation (11 available)
Tg(Lhx2-cre)1Lcar mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal optic vesicle formation ( J:176341 )
• vesicle development is normal to E9.5, although the number of apoptotic cells is increased
• degeneration of the optic vesicle is detected at E11.5; by E12.5, all neural structures in the eye are absent with no detectable lens structure

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory