Phenotypes for Ctnnb1 Gt(ROSA)26Sor H2az2 MGI:5308958 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ctnnb1^tm2Kem/Ctnnb1^tm2Kem Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
Genetic Background	involves: 129 * C57BL/6 * CBA/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm2Kem mutation (1 available); any Ctnnb1 mutation (51 available)
Gt(ROSA)26Sor^tm1Sor mutation (10 available); any Gt(ROSA)26Sor mutation (1062 available)
H2az2^{Tg(Wnt1-cre)11Rth} mutation (2 available); any H2az2 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

absent mandible ( J:178971 )

• at E12.5

absent maxilla ( J:178971 )

• at E12.5

small pharyngeal arch ( J:178971 )

• rudimentary at E12.5

nervous system

absent midbrain-hindbrain boundary ( J:178971 )

• absent at E10.5

absent midbrain ( J:178971 )

• absence of midbrain structures at E10.5

absent hindbrain ( J:178971 )

• absence of hindbrain structures at E10.5

embryo

small pharyngeal arch ( J:178971 )

• rudimentary at E12.5

skeleton

absent mandible ( J:178971 )

• at E12.5

absent maxilla ( J:178971 )

• at E12.5

growth/size/body

absent mandible ( J:178971 )

• at E12.5

absent maxilla ( J:178971 )

• at E12.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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