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Phenotypes Associated with This Genotype
Genotype
MGI:5308955
Allelic
Composition
Ctnnb1tm2Kem/Ctnnb1tm2Kem
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background
involves: 129 * C57BL/6 * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1tm2Kem mutation (1 available); any Ctnnb1 mutation (49 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• disruption of apical neural tube morphology leading to migration of cells into the neural canal
• malformed telencephalic lobes at E12.5

craniofacial

embryo
• disruption of apical neural tube morphology leading to migration of cells into the neural canal

cellular


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory