Analysis Tools
mortality/aging
| N |
• mutants are viable and born at the expected Mendelian ratios
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growth/size/body
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• decreased body weight compared to GarsC201R heterozygotes
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nervous system
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• the motor branch of the femoral nerve is smaller and axon numbers are reduced
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• mutants exhibit more severe neuromuscular junction defects than either allele as a heterozygote, with a majority of NMJs partially or fully denervated and very few that are fully innervated
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