Phenotypes Associated with This Genotype

Genotype
MGI:5306615

• Allelic Composition: Kras^tm5Tyj/Kras⁺; Trp53^tm1.1Dgk/Trp53^tm1.1Dgk
• Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased tumor growth/size ( J:180576 )

• lung tumors from mice injected with cre- and flpo-expressing adenoviruses exhibit a doubling time of 2 weeks

increased lung adenocarcinoma incidence ( J:180576 )

• high-grade ling adenocarcinomas as early as 8 weeks after injection with cre- and flpo-expressing adenoviruses

increased sarcoma incidence ( J:180576 )

• extremity sarcomas as early as 8 weeks after injection with cre- and flpo-expressing adenoviruses

respiratory system

increased lung adenocarcinoma incidence ( J:180576 )

• high-grade ling adenocarcinomas as early as 8 weeks after injection with cre- and flpo-expressing adenoviruses