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Phenotypes Associated with This Genotype
Genotype
MGI:5306351
Allelic
Composition		 Kitltm2.1Sjm/Kitltm2.2Sjm
Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic
Background		 involves: BALB/cJ * C57BL * CBA/Ca * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Commd10Tg(Vav1-icre)A2Kio mutation (3 available); any Commd10 mutation (24 available)
Kitltm2.1Sjm mutation (1 available); any Kitl mutation (92 available)
Kitltm2.2Sjm mutation (0 available); any Kitl mutation (92 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:180431 )
N
• exhibit normal blood cell counts, bone marrow composition, bone marrow and spleen cellularity, and reconstitution capacity
decreased hematopoietic cell number ( J:180431 )
• 2-fold as in Kitltm2.2Sjm heterozygotes in the bone marrow

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory